Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757454 | 0.77 | CASP6 (0.40) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL8123714 | 0.75 | CASP6 (0.37) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL85584 | 0.72 | TDP1 (0.53) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL9735458 | 0.71 | NR1H4 (0.39) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL9201653 | 0.71 | NR1H4 (0.37) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL8120777 | 0.71 | CASP6 (0.37) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL5415229 | 0.71 | TDP1 (0.52) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL9372313 | 0.70 | CASP6 (0.39) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL5166507 | 0.70 | MAPT (0.57) | CASP6TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL14864868 | 0.70 | POLB (0.51) | CASP6TDP1POLBAPEX1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321175-A1 | Indane derivatives | BEECHAM GROUP PLC (GB) | 1989-06-21 | — | — | EP | disclosed |