Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28405351 | 0.86 | TDP1 (0.44) | GPR35TDP1MAPTMEN1KMT2A | |
| SCHEMBL7499271 | 0.85 | APP (0.42) | GPR35TDP1MAPTMEN1KMT2A | |
| SCHEMBL4375603 | 0.84 | ALDH1A1 (0.53) | GPR35TDP1MEN1KMT2AMAPK1 | |
| SCHEMBL27636988 | 0.83 | TDP1 (0.41) | GPR35TDP1MAPTGAAMEN1 | |
| SCHEMBL41322 | 0.74 | GPR35 (0.54) | GPR35TDP1MAPTGAAMEN1 | |
| SCHEMBL14880715 | 0.74 | TSHR (0.48) | TDP1MAPTGAAMEN1KMT2A | |
| SCHEMBL1206907 | 0.74 | ALDH1A1 (0.53) | GPR35TDP1GAAMEN1KMT2A | |
| SCHEMBL4649696 | 0.73 | EIF4E (0.39) | GPR35TDP1MAPTMEN1KMT2A | |
| SCHEMBL8138795 | 0.73 | ALDH1A1 (0.45) | GPR35TDP1MAPTGAAMEN1 | |
| SCHEMBL27376059 | 0.73 | GPR35 (0.57) | GPR35TDP1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877808-A | ANTITHROMBOTICS | FOURNIER INNOVATION ET SYNERGIE (FR) | 1989-10-31 | — | — | US | disclosed |