Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880715 | 0.83 | TSHR (0.48) | TDP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28405351 | 0.82 | TDP1 (0.44) | TDP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8138795 | 0.82 | ALDH1A1 (0.45) | TDP1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4375603 | 0.80 | ALDH1A1 (0.53) | TDP1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL12472636 | 0.78 | NPC1 (0.51) | EIF4ETDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7499271 | 0.74 | APP (0.42) | TDP1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2331528 | 0.74 | ALDH1A1 (0.65) | EIF4ETDP1EGFRALDH1A1GPR35 | |
| SCHEMBL10511751 | 0.73 | GPR35 (0.44) | TDP1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL27636988 | 0.73 | TDP1 (0.41) | EIF4ETDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4649697 | 0.72 | TDP1 (0.40) | EIF4ETDP1MEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |