SCHEMBL105120

SCHEMBL105120

CC1(C)OB(c2cccc(C3(c4ccc(N(c5ccccc5)c5ccccc5)cc4)c4ccccc4-c4ccccc43)c2)OC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPL P06858 5/20 0.38
LIPG Q9Y5X9 5/20 0.38
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30
POLB P06746 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17816875 0.93 LIPG (0.45) LPLLIPGESR1ESR2MEN1
SCHEMBL22402080 0.91 LPL (0.37) LPLLIPGESR1ESR2MEN1
SCHEMBL23273089 0.90 LIPG (0.47) LPLLIPGESR1ESR2MEN1
SCHEMBL29603064 0.90 LIPG (0.44) LPLLIPGESR1ESR2MEN1
SCHEMBL17470489 0.90 LIPG (0.44) LPLLIPGESR1ESR2MEN1
SCHEMBL17816784 0.89 LIPG (0.43) LPLLIPGESR1ESR2MEN1
SCHEMBL12166505 0.88 LIPG (0.43) LPLLIPGESR1ESR2MEN1
SCHEMBL22173457 0.87 LIPG (0.52) LPLLIPGESR1ESR2MEN1
SCHEMBL20806383 0.86 LIPG (0.43) LPLLIPGESR1ESR2MEN1
SCHEMBL20964191 0.86 LIPG (0.39) LPLLIPGPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815418-B2 Compound including fluorenyl group for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2014-08-26 US disclosed
US-8815418-B2 Compound including fluorenyl group for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2014-08-26 US disclosed
EP-2431445-A2 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE COMPRISING SAME Cheil Industries Inc. (KR) 2012-03-21 EP disclosed
US-20120056171-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-03-08 US disclosed
US-20120056171-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120056171-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME PPOX, AOX1, DDT LPL 2004/4885LIPG 2418/4885ESR1 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.