Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024186 | 0.73 | NISCH (0.42) | MAOBMAOAGAANPSR1 | |
| SCHEMBL667761 | 0.73 | MAOA (0.45) | MAOBMAOAGAANPSR1OXTR | |
| SCHEMBL29438383 | 0.73 | MAOA (0.45) | MAOBMAOAGAANPSR1OXTR | |
| SCHEMBL3252690 | 0.72 | RAB9A (0.44) | MAOBMAOAGAANPSR1AURKA | |
| SCHEMBL30140866 | 0.69 | MAOA (0.48) | MAOBMAOAGAANPSR1OXTR | |
| SCHEMBL1939933 | 0.69 | MAOA (0.48) | MAOBMAOAGAANPSR1OXTR | |
| SCHEMBL311687 | 0.68 | MAOB (0.39) | MAOBMAOAGAANPSR1 | |
| SCHEMBL8150353 | 0.67 | MAOA (0.35) | MAOBMAOAGAANPSR1 | |
| SCHEMBL9087669 | 0.67 | KDM4E (0.42) | MAOBMAOAGAANPSR1 | |
| SCHEMBL3689696 | 0.67 | MAOA (0.38) | MAOBMAOAGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162592-B1 | HETEROCYCLIC AMINO COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1989-03-22 | — | — | EP | disclosed |
| EP-0162592-A1 | Heterocyclic amino compounds | GLAXO GROUP LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |