Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667761 | 0.73 | MAOA (0.45) | MAOAMAOBGAANPSR1 | |
| SCHEMBL29438383 | 0.73 | MAOA (0.45) | MAOAMAOBGAANPSR1 | |
| SCHEMBL334750 | 0.71 | MAOA (0.46) | MAOAMAOBGAANPSR1 | |
| SCHEMBL11339436 | 0.69 | MAOA (0.37) | MAOAMAOBGAANPSR1 | |
| SCHEMBL311687 | 0.68 | MAOB (0.39) | MAOAMAOBGAANPSR1 | |
| SCHEMBL9087669 | 0.67 | KDM4E (0.42) | MAOAMAOBGAANPSR1 | |
| SCHEMBL10512367 | 0.67 | MAOB (0.38) | MAOAMAOBGAANPSR1 | |
| SCHEMBL7060258 | 0.67 | MAOA (0.38) | MAOAMAOBGAANPSR1 | |
| SCHEMBL292788 | 0.66 | MAOA (0.50) | MAOAMAOBGAANPSR1 | |
| SCHEMBL30356272 | 0.66 | MAOA (0.50) | MAOAMAOBGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539739-B1 | PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-24 | — | — | EP | claimed |
| US-20040077684-A1 | Piperidinyl compounds that selectively bind integrins | JANSSEN PHARMACEUTICA, NV (BE) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077684-A1 | Piperidinyl compounds that selectively bind integrins | ITGB3, ITGAV, ITGA2B | MAOA 4735/4885MAOB 4570/4885GAA 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.