SCHEMBL1939933

SCHEMBL1939933

NC1=CCc2ccccc2O1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
LMNA P02545 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GAA P10253 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPKAPK2 P49137 1/20 0.35
HTR6 P50406 1/20 0.33
OXTR P30559 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NISCH Q9Y2I1 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30140866 1.00 MAOA (0.48) MAOAMAOBLMNANPC1RAB9A
SCHEMBL10869264 0.78 MAOB (0.43) MAOAMAOBLMNANPC1RAB9A
SCHEMBL292788 0.76 MAOA (0.50) MAOAMAOBLMNANPC1RAB9A
SCHEMBL30356272 0.76 MAOA (0.50) MAOAMAOBLMNANPC1RAB9A
SCHEMBL1862899 0.74 MAOA (0.48) MAOAMAOBLMNANPC1RAB9A
SCHEMBL2006248 0.74 MAOA (0.48) MAOAMAOBLMNANPC1RAB9A
SCHEMBL57273 0.74 MAOA (0.48) MAOAMAOBLMNANPC1RAB9A
SCHEMBL758245 0.74 MAOA (0.48) MAOAMAOBLMNANPC1RAB9A
SCHEMBL753891 0.74 MAOA (0.48) MAOAMAOBLMNANPC1RAB9A
SCHEMBL292480 0.74 MAOA (0.48) MAOAMAOBLMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843669-A Amino benzopyran cyanine compound and application thereof 浙江大学长三角智慧绿洲创新中心 2024-04-09 CN claimed
CN-112939919-B 2-aminobenzopyran compound and application thereof in pesticide 西华大学 2023-02-03 CN claimed
WO-2023008989-A1 HETEROGENEOUS SOLID CATALYST FILM FOR 2-AMINO-4H-CHROMENE SYNTHESIS UNIVERSITÉ IBN TOFAIL (MA) 2023-02-02 WO claimed
CN-112939919-A 2-aminobenzopyran compound and application thereof in pesticide 西华大学 2021-06-11 CN claimed
CN-103788050-B A kind of green catalysis prepares the method for 2-amino-4H-chromene derivative ANHUI UNIVERSITY OF TECHNOLOGY (CN) 2015-12-02 CN claimed
CN-102786504-A Asymmetric synthesis method of 2-amino-4H-benzopyran compound UNIV EAST CHINA NORMAL 2012-11-21 CN claimed
EP-2231794-B1 INKS FOR DIGITAL PRINTING ON CERAMIC MATERIALS, A PROCESS FOR DIGITAL PRINTING ON CERAMIC MATERIALS USING SAID INKS, AND CERAMIC MATERIALS OBTAINED BY MEANS OF SAID PRINTING PROCESS METCO S R L (IT) 2011-06-15 EP claimed
EP-1535918-B1 PROCESS FOR PRODUCING AMINOBENZOPYRAN COMPOUND NISSAN CHEMICAL IND LTD (JP) 2010-11-03 EP claimed
US-7683189-B2 Process for producing aminobenzopyran compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-03-23 US claimed
WO-2010002075-A1 METHODS FOR PREPARING AMIDE DERIVATIVES PHARMACOSTECH CO., LTD. (KR) 2010-01-07 WO claimed
US-7015328-B2 Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. (US) 2006-03-21 US claimed
CN-1678603-A Process for producing aminobenzopyran compound NISSAN CHEMICAL IND LTD (JP) 2005-10-05 CN claimed
US-20050192444-A1 Process for producing aminobenzopyran compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-01 US claimed
EP-1535918-A1 PROCESS FOR PRODUCING AMINOBENZOPYRAN COMPOUND Nissan Chemical Industries, Ltd. (JP) 2005-06-01 EP claimed
EP-1392283-A4 SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASE ACTIVATORS CYTOVIA INC (US) 2004-10-20 EP claimed
EP-1392283-A1 SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASES ACTIVATORS Cytovia, Inc. (US) 2004-03-03 EP claimed
US-20030114485-A1 Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-06-19 US claimed
WO-2002092076-A1 SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASES ACTIVATORS CYTOVIA, INC. (US) 2002-11-21 WO claimed
US-5851701-A Atom lithographic mask having diffraction grating and attenuated phase shifters MICRON TECHNOLOGY, INC. (US) 1998-12-22 US claimed
EP-0300908-B1 BENZOPYRAN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM RHONE-POULENC SANTE (FR) 1992-03-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050192444-A1 Process for producing aminobenzopyran compound ALDH7A1, ACMSD, MANBA MAOA 336/4885MAOB 129/4885LMNA 4580/4885
US-20030114485-A1 Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof CASP7, CASP1, CASP5 MAOA 1929/4885MAOB 1822/4885LMNA 293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.