SCHEMBL10512972

SCHEMBL10512972

CC(C)N1CCN(c2cccc3ccoc23)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.52
DRD2 P14416 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10515391 0.98 HTR1A (0.51) HTR1ADRD2
SCHEMBL10514753 0.82
SCHEMBL10514032 0.81 HTR1A (0.58) HTR1ADRD2
SCHEMBL30992343 0.80 HTR1A (0.53) HTR1ADRD2
SCHEMBL13239012 0.80 HTR1A (0.53) HTR1ADRD2
SCHEMBL10514073 0.79 P4HB (0.38) HTR1ADRD2
SCHEMBL10514838 0.78 HTR1A (0.42) HTR1ADRD2
SCHEMBL2545146 0.78 HTR3E (0.56) HTR1A
Hydrochloric Acid SCHEMBL10523385 0.76 KDM4E (0.57)
SCHEMBL10514665 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190472-B1 NEW PHARMACEUTICAL COMPOSITIONS HAVING ANTI-PSYCHOTIC PROPERTIES DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-07-12 EP claimed
EP-0190472-A1 New pharmaceutical compositions having anti-psychotic properties DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1986-08-13 EP claimed
EP-0190472-B1 NEW PHARMACEUTICAL COMPOSITIONS HAVING ANTI-PSYCHOTIC PROPERTIES DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-07-12 EP disclosed
US-4782061-A CENTRAL NERVOUS SYSTEM DISORDERS DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1988-11-01 US disclosed
EP-0190472-A1 New pharmaceutical compositions having anti-psychotic properties DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1986-08-13 EP disclosed