Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30992343 | 1.00 | HTR1A (0.53) | HTR1ADRD2 | |
| SCHEMBL5756036 | 0.84 | — | — | |
| SCHEMBL10514753 | 0.84 | — | — | |
| SCHEMBL2545146 | 0.83 | HTR3E (0.56) | HTR1A | |
| Hydrochloric Acid SCHEMBL10523385 | 0.81 | KDM4E (0.57) | — | |
| SCHEMBL6583762 | 0.80 | — | — | |
| SCHEMBL10512972 | 0.80 | HTR1A (0.52) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL10515391 | 0.79 | HTR1A (0.51) | HTR1ADRD2 | |
| SCHEMBL7840531 | 0.78 | HTR1A (0.53) | HTR1ADRD2 | |
| SCHEMBL10514665 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998539-B2 | Substituted aminoquinolones as DGKalpha inhibitors for immune activation | BAYER AKTIENGESELLSCHAFT (DE) | 2024-06-04 | — | — | US | disclosed |
| US-RE41425-E1 | used for the treatment of affective disorders or diseases of the central nervous system caused by disturbances in either the dopaminergic or serotinergic systems, such as schizophrenia | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 2010-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11998539-B2 | Substituted aminoquinolones as DGKalpha inhibitors for immune activation | DGKK, DGKG, DGKA | HTR1A 4284/4885DRD2 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.