Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 2/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436206 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HTTLMNASMN1; SMN2COMT | |
| SCHEMBL9526222 | 0.74 | PCSK9 (0.47) | ALDH1A1HTTLMNASMN1; SMN2HPGD | |
| SCHEMBL9526242 | 0.74 | COMT (0.49) | ALDH1A1SMN1; SMN2COMTDDB1CRBN | |
| SCHEMBL3424995 | 0.74 | TSHR (0.56) | ALDH1A1HTTLMNASMN1; SMN2HPGD | |
| SCHEMBL347805 | 0.73 | PCSK9 (0.53) | ALDH1A1HTTLMNASMN1; SMN2COMT | |
| SCHEMBL10059749 | 0.72 | SMN1; SMN2 (0.60) | ALDH1A1HTTSMN1; SMN2COMTDDB1 | |
| SCHEMBL28615315 | 0.72 | PCSK9 (0.44) | ALDH1A1HTTLMNASMN1; SMN2COMT | |
| SCHEMBL4794282 | 0.71 | COMT (0.50) | ALDH1A1HTTLMNASMN1; SMN2COMT | |
| SCHEMBL11374766 | 0.70 | ALDH1A1 (0.40) | ALDH1A1HTTLMNAHPGDTSHR | |
| SCHEMBL17916163 | 0.69 | ALDH1A1 (0.52) | ALDH1A1HTTCOMTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304057-A2 | Pyridinone derivatives, and agricultural and horticultural fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-02-22 | — | — | EP | disclosed |