Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356920 | 0.89 | HTR2C (0.46) | KMT2AAGTR2HTR2CCYP3A4ACE | |
| SCHEMBL9327739 | 0.85 | CTSL (0.49) | KMT2AL3MBTL1KLK7JAK2CTSL | |
| SCHEMBL9356665 | 0.84 | HTR2C (0.46) | KMT2AAGTR2HTR2CHTTCYP3A4 | |
| SCHEMBL10514141 | 0.84 | HTR2C (0.46) | KMT2AAGTR2HTR2CHTTCYP3A4 | |
| SCHEMBL629532 | 0.83 | FKBP1A (0.46) | KMT2AL3MBTL1KLK7JAK2JAK1 | |
| SCHEMBL12684557 | 0.83 | FKBP1A (0.46) | KMT2AL3MBTL1KLK7JAK2JAK1 | |
| SCHEMBL15457809 | 0.83 | FKBP1A (0.46) | KMT2AL3MBTL1KLK7JAK2JAK1 | |
| SCHEMBL10607382 | 0.83 | CTSL (0.49) | KMT2AKLK7JAK2CTSLCYP3A4 | |
| SCHEMBL10788524 | 0.81 | DPP4 (0.39) | KMT2AHTR2CCYP3A4ACEALOX15 | |
| SCHEMBL10437288 | 0.81 | ACE (0.41) | KMT2AL3MBTL1CYP3A4ACEALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320753-A2 | Derivatives of cyclic aminoacids, their preparation, compounds containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-21 | — | — | EP | disclosed |