Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 3/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10607382 | 0.98 | CTSL (0.49) | CTSLKMT2AACEMEN1CYP3A4 | |
| SCHEMBL9592654 | 0.85 | CTSL (0.54) | CTSLKMT2AACEMEN1CYP3A4 | |
| SCHEMBL9773233 | 0.85 | CTSL (0.54) | CTSLKMT2AACEMEN1CYP3A4 | |
| SCHEMBL10514501 | 0.85 | KMT2A (0.41) | CTSLKMT2AACEMEN1CYP3A4 | |
| SCHEMBL9256682 | 0.84 | CTSL (0.54) | CTSLKMT2AACEMEN1CYP3A4 | |
| SCHEMBL9732240 | 0.81 | ACE (0.51) | CTSLKMT2AACEMEN1CYP3A4 | |
| SCHEMBL11035731 | 0.81 | ACE (0.44) | KMT2AACEMEN1CYP3A4ALOX15 | |
| Trifluoroacetic Acid SCHEMBL10589143 | 0.80 | DPP4 (0.41) | KMT2AACEMEN1CYP3A4ALOX15 | |
| SCHEMBL11016674 | 0.79 | ACE (0.73) | KMT2AACEMEN1CYP3A4ALOX15 | |
| SCHEMBL9356920 | 0.78 | HTR2C (0.46) | KMT2AACEMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243645-B1 | Compounds having a nootropic activity, agents containing them and their use in the treatment and prophylaxis of cognitive malfunctions | HOECHST AG (DE) | 1994-03-16 | — | — | EP | disclosed |