Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501166 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL14394504 | 0.61 | HRH2 (0.44) | ALDH1A1LMNASMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL29528050 | 0.59 | TSHR (0.39) | ALDH1A1LMNASMN1; SMN2KDM4ETSHR | |
| SCHEMBL10162567 | 0.58 | HSD11B1 (0.72) | ALDH1A1L3MBTL1KDM4ETDP1TSHR | |
| SCHEMBL2133889 | 0.58 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2KDM4EPOLB | |
| SCHEMBL14607629 | 0.58 | MAPT (0.43) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7131839 | 0.58 | NPC1 (0.86) | ALDH1A1SMN1; SMN2L3MBTL1TDP1TSHR | |
| SCHEMBL21322119 | 0.58 | GRM5 (0.60) | L3MBTL1KDM4ETDP1TSHRPOLB | |
| SCHEMBL3035973 | 0.58 | POLB (0.76) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL10130744 | 0.58 | NPC1 (0.67) | ALDH1A1SMN1; SMN2L3MBTL1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-A1 | Propane derivatives | KOWA COMPANY, LTD. (JP) | 1989-09-06 | — | — | EP | claimed |