Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502763 | 0.76 | FABP6 (0.43) | ALDH1A1SMN1; SMN2KDM4ETSHRPOLB | |
| SCHEMBL9502829 | 0.74 | SIGMAR1 (0.41) | ALDH1A1LMNASMN1; SMN2KDM4EPOLB | |
| SCHEMBL9502196 | 0.73 | CYP2D6 (0.47) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL10518201 | 0.70 | CXCR4 (0.46) | SMN1; SMN2TDP1MEN1KMT2A | |
| SCHEMBL9504119 | 0.70 | CYP2D6 (0.44) | ALDH1A1LMNASMN1; SMN2KDM4ETSHR | |
| SCHEMBL9502157 | 0.68 | GPBAR1 (0.47) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9501464 | 0.66 | BCHE (0.38) | ALDH1A1LMNAL3MBTL1KDM4ETDP1 | |
| SCHEMBL31669011 | 0.61 | CYP2C9 (0.41) | POLBMAPTGAACYP2D6CYP2C9 | |
| SCHEMBL28927208 | 0.61 | CYP2C9 (0.41) | POLBMAPTGAACYP2D6CYP2C9 | |
| SCHEMBL10130744 | 0.60 | NPC1 (0.67) | ALDH1A1SMN1; SMN2L3MBTL1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | claimed |
| US-4960883-A | Cardiovascular disorders | KOWA COMPANY, LTD. (JP) | 1990-10-02 | — | — | US | claimed |