Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ME2 | P23368 | 1/20 | 0.51 |
| ▸ | ME1 | P48163 | 1/20 | 0.51 |
| ▸ | ME3 | Q16798 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119956 | 0.84 | NPC1 (0.65) | GRM5NPC1TDP1TEAD3MAPT | |
| SCHEMBL7280507 | 0.81 | GRM5 (0.70) | GRM5NPC1TDP1L3MBTL1ME2 | |
| SCHEMBL30860040 | 0.80 | TIPARP (0.52) | GRM5 | |
| SCHEMBL8646464 | 0.80 | SPHK1 (0.45) | GRM5NPC1TDP1TEAD3L3MBTL1 | |
| SCHEMBL24706552 | 0.79 | L3MBTL1 (0.55) | GRM5NPC1L3MBTL1GAAMAPT | |
| SCHEMBL11271699 | 0.79 | NOTUM (0.63) | GRM5NPC1TDP1L3MBTL1ME2 | |
| SCHEMBL23693070 | 0.78 | L3MBTL1 (0.62) | GRM5NPC1TDP1L3MBTL1GAA | |
| SCHEMBL508419 | 0.78 | TSHR (0.56) | TDP1L3MBTL1MAPTTSHR | |
| SCHEMBL7708032 | 0.78 | TSHR (0.56) | TDP1L3MBTL1TSHR | |
| SCHEMBL24706551 | 0.78 | L3MBTL1 (0.61) | NPC1L3MBTL1GAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511266-B1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | UNIV CALIFORNIA (US) | 2019-09-04 | — | — | EP | disclosed |