⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Squamolone SCHEMBL28367081 | 0.98 | LMNA (0.57) | — | |
| SCHEMBL4702017 | 0.93 | LMNA (0.52) | — | |
| SCHEMBL1424272 | 0.91 | LMNA (0.50) | — | |
| SCHEMBL6538147 | 0.85 | — | — | |
| SCHEMBL2594237 | 0.80 | LMNA (0.64) | — | |
| SCHEMBL8579741 | 0.79 | — | — | |
| SCHEMBL21077570 | 0.79 | LMNA (0.52) | — | |
| SCHEMBL31098685 | 0.79 | LMNA (0.42) | — | |
| Hydroxyamine SCHEMBL7974682 | 0.79 | LMNA (0.57) | — | |
| SCHEMBL13792789 | 0.79 | LMNA (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100534990-C | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-02 | — | — | CN | claimed |
| US-7067549-B2 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2006-06-27 | — | — | US | claimed |
| US-20050192292-A1 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2005-09-01 | — | — | US | claimed |
| CN-1610678-A | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS LTD (CH) | 2005-04-27 | — | — | CN | claimed |
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | claimed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | claimed |
| EP-0373226-B1 | Carbamoyl-2-pyrrolidinone compounds | TAIHO PHARMACEUTICAL CO LTD (JP) | 1994-06-15 | — | — | EP | claimed |
| US-5229402-A | Improving cerebral function | TAIHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0373226-A1 | Carbamoyl-2-pyrrolidinone compounds | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1990-06-20 | — | — | EP | claimed |
| EP-0187052-B1 | ADAMANTAN AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | S.A. PANMEDICA Société dite: (FR) | 1990-01-31 | — | — | EP | claimed |
| EP-0177450-B1 | PROCESS FOR THE PREPARATION OF CYCLOHEXANE DIONE CARBOXYLIC-ACID DERIVATIVES WITH A HERBICIDAL AND PLANT-GROWTH REGULATING EFFECT | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | claimed |
| EP-0187052-A1 | Adamantan amine derivatives, process for their preparation and medicines containing them | S.A. PANMEDICA Société dite: (FR) | 1986-07-09 | — | — | EP | claimed |
| EP-0037990-A1 | Phenyl quinolizidines, corresponding pharmaceutical preparations, the preparation of the active compounds and corresponding starting compounds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-10-21 | — | — | EP | claimed |
| JP-1265071-A | — | — | None | — | — | JP | disclosed |
| CN-121974890-A | Crystalline CSF-1R inhibitor acid salt and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2026-05-05 | — | — | CN | disclosed |
| EP-4637688-A1 | ORAL CARE COMPOSITIONS | Colgate-Palmolive Company (US) | 2025-10-29 | — | — | EP | disclosed |
| US-4124594-A | REACTING AMINO-HYDROXYBUTYRIC ACID WITH A SILYLATING AGENT FOLLOWED BY REACTION WITH A HALOGENATED ESTER, CYCLIZATION | I.S.F. SPA (IT) | 1978-11-07 | — | — | US | disclosed |
| US-4003911-A | ANTISECRETORY AGENTS, OXYTOCICS, BRONCHODILATORS, PLASTICIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
| US-3996288-A | Method of producing aldehydes by hydroformylation | AJINOMOTO CO., INC. (JA) | 1976-12-07 | — | — | US | disclosed |
| US-3948943-A | THERAPEUTIC, DERMATOLOGICAL, COSMETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-06 | — | — | US | disclosed |