Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516548 | 1.00 | PPM1B (0.40) | PPM1BNLRP3CA12CA1CA2 | |
| SCHEMBL10516538 | 1.00 | PPM1B (0.40) | PPM1BNLRP3CA12CA1CA2 | |
| SCHEMBL14330313 | 0.86 | PPM1B (0.36) | PPM1BNLRP3CA12CA1CA2 | |
| SCHEMBL4624809 | 0.78 | NLRP3 (0.34) | PPM1BNLRP3CA12CA1CA2 | |
| SCHEMBL8836411 | 0.77 | CA12 (0.35) | NLRP3CA12CA1CA2CA9 | |
| Bicarbonate SCHEMBL29160648 | 0.75 | PPP5C (0.35) | PPM1BNLRP3CA12CA1CA2 | |
| SCHEMBL13564252 | 0.73 | SLC6A3 (0.35) | PPM1BNLRP3CA12CA1CA2 | |
| SCHEMBL13003493 | 0.73 | — | — | |
| SCHEMBL17407677 | 0.72 | ALDH1A1 (0.36) | NLRP3CA12CA1CA2CA9 | |
| SCHEMBL24912279 | 0.72 | ALDH1A1 (0.43) | NLRP3HSD17B10ALDH1A1LMNAPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330992-A2 | Novel cyclobutane Derivatives, processes for their preparation and pharmaceutical compositions comprising them | Nippon Kayaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |