Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773489 | 0.78 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2ALDH1A1CA12CA1 | |
| SCHEMBL9352633 | 0.73 | CA1 (0.58) | LMNASMN1; SMN2MAPK1ALDH1A1CA12 | |
| Indapamide SCHEMBL29372690 | 0.73 | CA1 (1.00) | LMNASMN1; SMN2TDP1ALDH1A1CA12 | |
| Indapamide SCHEMBL163266 | 0.73 | CA1 (1.00) | LMNASMN1; SMN2TDP1ALDH1A1CA12 | |
| Indapamide SCHEMBL2329030 | 0.73 | CA1 (1.00) | LMNASMN1; SMN2TDP1ALDH1A1CA12 | |
| Indapamide SCHEMBL41303 | 0.73 | CA1 (1.00) | LMNASMN1; SMN2TDP1ALDH1A1CA12 | |
| Indapamide SCHEMBL29377544 | 0.73 | CA1 (1.00) | LMNASMN1; SMN2TDP1ALDH1A1CA12 | |
| Indapamide SCHEMBL476213 | 0.73 | CA1 (1.00) | LMNASMN1; SMN2TDP1ALDH1A1CA12 | |
| Indapamide SCHEMBL29496872 | 0.73 | CA1 (1.00) | LMNASMN1; SMN2TDP1ALDH1A1CA12 | |
| Indapamide SCHEMBL3159715 | 0.72 | CA1 (0.98) | LMNASMN1; SMN2TDP1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61134382-A | — | — | None | — | — | JP | disclosed |
| EP-0186796-B1 | SULFAMOYLBENZOIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1989-09-27 | — | — | EP | disclosed |
| US-4650871-A | DIURETIC, URICOSURIC | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-03-17 | — | — | US | disclosed |
| EP-0186796-A1 | Sulfamoylbenzoic acid derivatives, process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |
| JP-S61134382-A | NOVEL SULFAMOYLBENZOIC ACID DERIVATIVE AND PRODUCTION THEREOF | KYORIN PHARMACEUT CO LTD | 1986-06-21 | — | — | JP | disclosed |