Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518596 | 0.78 | LMNA (0.58) | SMN1; SMN2LMNAHTTALDH1A1KDM4E | |
| SCHEMBL9352633 | 0.74 | CA1 (0.58) | SMN1; SMN2LMNAHTTCYP1A2CYP2C9 | |
| SCHEMBL8507747 | 0.72 | ALDH1A1 (0.57) | SMN1; SMN2CYP2C9NPSR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL27510542 | 0.71 | ALDH1A1 (0.53) | SMN1; SMN2CYP2C9NPSR1ALDH1A1KDM4E | |
| SCHEMBL7488520 | 0.71 | ALDH1A1 (0.59) | SMN1; SMN2CYP2C9NPSR1ALDH1A1KDM4E | |
| SCHEMBL10401973 | 0.71 | ALDH1A1 (0.56) | SMN1; SMN2CYP2C9NPSR1ALDH1A1KDM4E | |
| SCHEMBL9630198 | 0.70 | CA1 (0.73) | SMN1; SMN2LMNAHTTALDH1A1KDM4E | |
| SCHEMBL19319241 | 0.69 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAHTTCYP1A2CYP2C9 | |
| Tripamide SCHEMBL49666 | 0.69 | KDM4E (0.59) | SMN1; SMN2LMNAHTTNPSR1ALDH1A1 | |
| Tripamide SCHEMBL1651231 | 0.69 | KDM4E (0.59) | SMN1; SMN2LMNAHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62255479-A | — | — | None | — | — | JP | disclosed |
| JP-S62255479-A | NOVEL SULFAMOYLBENZOIC ACID DERIVATIVE AND PRODUCTION THEREOF | KYORIN PHARMACEUT CO LTD | 1987-11-07 | — | — | JP | disclosed |