Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521863 | 0.88 | LSS (0.50) | MAPTKMT2AALDH1A1LSSNOS1 | |
| SCHEMBL10521093 | 0.88 | LSS (0.47) | LSSNOS1NOS2ROCK1ROCK2 | |
| SCHEMBL10521322 | 0.87 | MAPT (0.55) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL10519264 | 0.86 | KMT2A (0.57) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL10519036 | 0.86 | ALDH1A1 (0.53) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL10519297 | 0.84 | MEN1 (0.55) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL10518331 | 0.84 | MAPT (0.62) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL10519488 | 0.81 | ALDH1A1 (0.52) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| Oxalic Acid SCHEMBL10622034 | 0.81 | ALDH1A1 (0.46) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL10519602 | 0.80 | ALDH1A1 (0.63) | MAPTKMT2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |