Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025764 | 0.86 | CA1 (0.46) | MAPTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL18156890 | 0.82 | ADRA2A (0.46) | MAPTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL526383 | 0.82 | MAPT (0.58) | MAPTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL1797711 | 0.79 | KIF11 (0.52) | MAPTADRA2AADRA2BADRA2CLMNA | |
| Hydrochloric Acid SCHEMBL9181167 | 0.79 | MAPT (0.56) | MAPTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL10261173 | 0.78 | MAPT (0.47) | MAPTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL10721177 | 0.76 | ESR1 (0.45) | MAPTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL10432350 | 0.76 | ABL1 (0.49) | NR3C2MAPTLMNAPTPN11ALDH1A1 | |
| SCHEMBL4597093 | 0.76 | HSD11B1 (0.44) | MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL16641018 | 0.74 | CA1 (0.50) | NR3C2LMNAPTPN11ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861810-A | DIEPOXIDES, MODULUS, TOUGHNESS, GLASS TRANSITION TEMPERATURE | SHELL OIL COMPANY (US) | 1989-08-29 | — | — | US | claimed |
| US-4861810-A | DIEPOXIDES, MODULUS, TOUGHNESS, GLASS TRANSITION TEMPERATURE | SHELL OIL COMPANY (US) | 1989-08-29 | — | — | US | disclosed |