Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | LTA4H | P09960 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520856 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LTA4HRAB9ANPC1MAPT | |
| SCHEMBL11838315 | 0.77 | LTA4H (0.62) | ALDH1A1LTA4HRAB9ANPC1MAPT | |
| SCHEMBL12495744 | 0.75 | ATP4A (0.67) | ALDH1A1LTA4HRAB9ANPC1MAPT | |
| SCHEMBL10519089 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LTA4HRAB9ANPC1MAPT | |
| SCHEMBL10520826 | 0.73 | ALDH1A1 (0.64) | ALDH1A1LTA4HRAB9ANPC1MAPT | |
| SCHEMBL21504858 | 0.73 | ALDH1A1 (0.53) | ALDH1A1LTA4HRAB9ANPC1MAPT | |
| SCHEMBL10521340 | 0.71 | SMN1; SMN2 (0.44) | ALDH1A1LTA4HRAB9ANPC1MAPT | |
| SCHEMBL5913878 | 0.71 | HSD17B10 (0.48) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL16003854 | 0.69 | ALDH1A1 (0.52) | ALDH1A1LTA4HRAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL308085 | 0.69 | HSD17B10 (0.47) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |