Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | FTO | Q9C0B1 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16609698 | 0.88 | CYP3A4 (0.48) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL31063932 | 0.88 | CYP3A4 (0.48) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL17581035 | 0.88 | FTO (0.63) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL25759008 | 0.88 | CYP3A4 (0.77) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL25633972 | 0.87 | CYP3A4 (0.54) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL10518377 | 0.87 | FTO (0.59) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL29386324 | 0.86 | CYP3A4 (0.74) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL1930643 | 0.86 | CYP3A4 (0.74) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL10145623 | 0.86 | CYP3A4 (0.65) | CYP3A4MAPTMEN1KMT2AHTT | |
| SCHEMBL13295494 | 0.85 | FTO (0.56) | CYP3A4MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174054-B1 | HEAT-SENSITIVE ELEMENT FOR USE IN A THERMAL IMAGING METHOD | POLAROID CORPORATION (US) | 1989-06-28 | — | — | EP | disclosed |
| US-4826976-A | THERMOCHROMISM | POLAROID CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| US-4602263-A | FOR OPTICAL RECORDING MEDIA | POLAROID CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0174054-A2 | Heat-sensitive element for use in a thermal imaging method | POLAROID CORPORATION (US) | 1986-03-12 | — | — | EP | disclosed |