SCHEMBL25633972

SCHEMBL25633972

COc1ccc(Nc2ccc3c(c2)Oc2cc(Nc4ccc(OC)cc4C)ccc2C32OC(=O)c3ccccc32)c(C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.54
MAPT P10636 5/20 0.53
LMNA P02545 5/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
HTT P42858 2/20 0.53
USP2 O75604 1/20 0.53
ALDH1A1 P00352 1/20 0.53
FTO Q9C0B1 6/20 0.49
TDP1 Q9NUW8 2/20 0.49
CYP2C19 P33261 2/20 0.49
HPGD P15428 1/20 0.49
RECQL P46063 1/20 0.49
BLM P54132 1/20 0.49
SMAD3 P84022 1/20 0.49
PRMT1 Q99873 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
GAA P10253 1/20 0.48
NPSR1 Q6W5P4 3/20 0.44
POLB P06746 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10520141 0.87 CYP3A4 (0.61) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL1639350 0.85 FTO (0.51) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL29386324 0.83 CYP3A4 (0.74) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL1930643 0.83 CYP3A4 (0.74) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL1640227 0.82 FTO (0.47) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL1208665 0.81 FTO (0.51) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL1639333 0.81 FTO (0.47) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL1639993 0.81 FTO (0.47) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL10520882 0.81 FTO (0.53) CYP3A4MAPTLMNAMEN1KMT2A
SCHEMBL1638516 0.81 FTO (0.46) CYP3A4MAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150254-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-05-18 US disclosed