Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 6/20 | 0.40 |
| ▸ | RXRA | P19793 | 5/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520186 | 1.00 | GABRA1 (0.40) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL8160158 | 0.78 | RXRA (0.55) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL8160160 | 0.78 | RXRA (0.55) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL2965925 | 0.73 | GABRA1 (0.48) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL8159340 | 0.72 | TP53 (0.37) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL8159338 | 0.72 | TP53 (0.37) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL29188793 | 0.69 | TDP1 (0.51) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL271349 | 0.69 | RXRA (0.42) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL23495534 | 0.68 | CES2 (0.58) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL16179592 | 0.68 | GABRA1 (0.52) | GABRA1GABRB2RXRBRXRARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1279910-A | — | — | None | — | — | JP | disclosed |
| JP-H01279910-A | POLY(3,5-DI-TERT-BUTYL-4-HYDROXYPHENYLACETYLENE) AND MAGNETIC MATERIAL OF ORGANIC POLYMER | TSUCHIDA HIDETOSHI | 1989-11-10 | — | — | JP | disclosed |