SCHEMBL271349

SCHEMBL271349

CC(C)(C)c1cc(C(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 6/20 0.42
RXRB P28702 6/20 0.42
RXRG P48443 3/20 0.42
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
ACHE P22303 3/20 0.41
HDAC3 O15379 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC1 Q13547 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
BLM P54132 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2965925 0.95 GABRA1 (0.48) RXRARXRBRXRGGABRA1GABRB2
SCHEMBL1530374 0.87 NOTUM (0.46) SMN1; SMN2MAPTHSD17B10TDP1POLB
SCHEMBL2562131 0.81 EPHX2 (0.39) RXRARXRBRXRGACHEHDAC3
Ethane SCHEMBL29138437 0.79 ALDH1A1 (0.37) HDAC6TDP1ALDH1A1
SCHEMBL38576 0.79 ALDH1A1 (0.40) TP53ALOX15TDP1ALDH1A1
SCHEMBL1360237 0.79 ACHE (0.62) RXRARXRBACHEHDAC3HDAC6
SCHEMBL29540544 0.79 ACHE (0.62) RXRARXRBACHEHDAC3HDAC6
SCHEMBL13234298 0.78 RXRA (0.38) RXRARXRBRXRGGABRA1GABRB2
SCHEMBL1204142 0.78 CA5A (0.48) RXRARXRBRXRGGABRA1GABRB2
SCHEMBL166878 0.78 RXRB (0.59) RXRARXRBRXRGGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957156-A Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-08-30 CN claimed
EP-0760251-A1 A membrane and method for the separation of aromatic hydrocarbons from a mixture of various aromatic hydrocarbons or from a mixture of such aromatic hydrocarbons and non-aromatic hydrocarbons NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1997-03-05 EP claimed
EP-0693962-A1 ALKYL SUBSTITUTED AROMATIC POLYESTER GAS SEPARATION MEMBRANES L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1996-01-31 EP claimed
WO-1994023830-A1 ALKYL SUBSTITUTED AROMATIC POLYESTER GAS SEPARATION MEMBRANES L'Air Liquide Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) 1994-10-27 WO claimed
US-5352273-A Permeability, selectivity E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-04 US claimed
US-5073176-A Permselective E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-17 US claimed
US-4973659-A HEAR RESISTANT FILMS, FIBERS, COMPOSITES AMOCO CORPORATION (US) 1990-11-27 US claimed
US-4973660-A Polyamide of diamino-t-butyltoluene AMOCO CORPORATION (US) 1990-11-27 US claimed
US-4946934-A Useful for fiber making, coatings and films AMOCO CORPORATION (US) 1990-08-07 US claimed
EP-0263593-A2 Melt-processable polymeric materials based on 5-t-butalisophthalic acid AMOCO CORPORATION (US) 1988-04-13 EP claimed
JP-8151372-A None JP disclosed
JP-4265135-A None JP disclosed
WO-2025128333-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
WO-2025128334-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
WO-2025128332-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
US-4564705-A POLYAMIDE, POLYUREA AND POLYURETHANE MONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-14 US disclosed
US-4451642-A Bis(aminoneopentyl) aromatics and polyamides derived therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-29 US disclosed
US-4214071-A Amide-imide polymers WESTINGHOUSE ELECTRIC CORP. (US) 1980-07-22 US disclosed
US-4130579-A Bis(2-methyl-2-cyanopropyl) aromatics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-19 US disclosed
US-3996202-A Process for the preparation of sulfonate group containing aromatic polyamides HOECHST AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed