Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033011 | 0.82 | CYP2C19 (0.47) | POLBMAPK1 | |
| SCHEMBL15075374 | 0.81 | ALOX15 (0.49) | POLBTSHRMAPK1 | |
| SCHEMBL15071609 | 0.77 | CYP1A2 (0.56) | L3MBTL1TP53MAPK1 | |
| SCHEMBL28064034 | 0.76 | CYP1A2 (0.57) | — | |
| SCHEMBL19969448 | 0.75 | RXFP1 (0.59) | — | |
| SCHEMBL9287679 | 0.74 | ADORA2A (0.53) | ADORA2B | |
| SCHEMBL19969451 | 0.73 | RXFP1 (0.57) | — | |
| SCHEMBL8004115 | 0.73 | LMNA (0.55) | LMNANPSR1ADORA2BL3MBTL1TP53 | |
| SCHEMBL7606568 | 0.71 | CYP1A2 (0.50) | LMNANPSR1ADORA2BL3MBTL1TP53 | |
| SCHEMBL28033009 | 0.71 | MAPK1 (0.59) | NPSR1MAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198190-B1 | COMPOUNDS HAVING ANTIPLATELET AGGREGATION ACTIVITY, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELLEM INDUSTRIA FARMACEUTICA S.p.A. (IT) | 1989-05-31 | — | — | EP | disclosed |
| US-4737502-A | DIMETHYLXANTHINYL-SUBSTITUTED 4,5,6,7-TETRAHYDROTHIENO(3,2-C)P PYRIDINES | ELLEM INDUSTRIA FARMACEUTICA S.P.A. (IT) | 1988-04-12 | — | — | US | disclosed |
| EP-0199190-A2 | Separating element for separating solid particles, suspended in a gaseous current, by centrifugal force in a cylindrical whirl chamber | Anton Piller GmbH & Co. KG (DE) | 1986-10-29 | — | — | EP | disclosed |
| EP-0198190-A2 | Compounds having antiplatelet aggregation activity, a process for the preparation thereof and pharmaceutical compositions containing them | ELLEM INDUSTRIA FARMACEUTICA S.p.A. (IT) | 1986-10-22 | — | — | EP | disclosed |