SCHEMBL105221

SCHEMBL105221

O=C(OC(=O)C1CC1)C1CC1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ELANE P08246 1/20 0.35
MEN1 O00255 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.33
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL386768 0.90 CES2 (0.50) KMT2ASMN1; SMN2HTTTDP1ELANE
SCHEMBL6113076 0.90 SMN1; SMN2 (0.52) KMT2ASMN1; SMN2HTTTDP1L3MBTL1
SCHEMBL27553353 0.87 CES2 (0.55) KMT2ASMN1; SMN2HTTTDP1ELANE
SCHEMBL11862575 0.87 CES2 (0.55) KMT2ASMN1; SMN2HTTTDP1ELANE
SCHEMBL6939791 0.87 CES2 (0.55) KMT2ASMN1; SMN2HTTTDP1ELANE
SCHEMBL2828979 0.87 LMNA (0.48) SMN1; SMN2TDP1RAB9ATP53PLG
SCHEMBL248821 0.87 CES2 (0.55) KMT2ASMN1; SMN2HTTTDP1ELANE
SCHEMBL776566 0.87 CES2 (0.55) KMT2ASMN1; SMN2HTTTDP1ELANE
Bicarbonate SCHEMBL7635343 0.85 SMN1; SMN2 (0.48) KMT2ASMN1; SMN2HTTTDP1ELANE
SCHEMBL2197391 0.85 KMT2A (0.40) KMT2ASMN1; SMN2HTTTDP1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136781-A ROR 1-targeted inhibitor and synthesis method and application thereof 北京大学 2025-06-13 CN claimed
WO-2024094637-A1 PROCESS FOR THE PREPARATION OF CYCLIC KETONES ARXADA AG (CH) 2024-05-10 WO claimed
CN-117820239-A Novel CSF1R inhibitor and preparation method and application thereof 四川大学华西医院 2024-04-05 CN claimed
CN-117222615-A Process for the preparation of phenyl ketones 阿尔萨达股份公司 2023-12-12 CN claimed
US-11840507-B2 Process for the preparation of phenyl ketones ARXADA AG (CH) 2023-12-12 US claimed
US-20230242469-A1 Process for the Preparation of Phenyl Ketones ARXADA AG (CH) 2023-08-03 US claimed
EP-4200271-A1 PROCESS FOR THE PREPARATION OF PHENYL KETONES Arxada AG (CH) 2023-06-28 EP claimed
WO-2022038098-A1 PROCESS FOR THE PREPARATION OF PHENYL KETONES ARXADA AG (CH) 2022-02-24 WO claimed
CN-113045793-A Medical hemostatic sponge material and preparation method thereof 宁波因天之序生物科技有限公司 2021-06-29 CN claimed
WO-2020132057-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION (US) 2020-06-25 WO claimed
US-20200203711-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-06-25 US claimed
EP-0061880-B1 PROCESS FOR PREPARING RACEMIZED CYCLOPROPANECARBOXYLIC ACIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-19 EP claimed
US-4485257-A TREATMENT WITH A LEWIS ACID; INSESTICIDAL USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-27 US claimed
EP-0061880-A1 Process for preparing racemized cyclopropanecarboxylic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-10-06 EP claimed
US-4175094-A REACTING AN AROMATIC ALDEHYDE AND AN ACID ANHYDRIDE SHELL OIL COMPANY (US) 1979-11-20 US claimed
JP-61277653-A None JP disclosed
JP-57163341-A None JP disclosed
US-3935211-A CNS DEPRESSANT AMERICAN CYANAMID COMPANY (US) 1976-01-27 US disclosed
US-3906097-A Method of producing a depressant effect using 5-cyclopropyl-1,2,4-oxadiazol-3-yl diazines AMERICAN CYANAMID CO 1975-09-16 US disclosed
US-3857843-A CYCLOPROPYL 1,2,4-OXADIAZOLYLDIAZINES AMERICAN CYANAMID CO 1974-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242469-A1 Process for the Preparation of Phenyl Ketones PAH, PDK4, PKM KMT2A 869/4885SMN1; SMN2 4151/4885HTT 650/4885
US-11840507-B2 Process for the preparation of phenyl ketones PAH, PDK4, PKM KMT2A 869/4885SMN1; SMN2 4151/4885HTT 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.