Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527739 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL27821122 | 0.79 | GABRP (0.48) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL5135351 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL28786423 | 0.78 | OXER1 (0.60) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL7869164 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL27452778 | 0.73 | MCL1 (0.53) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL3743077 | 0.73 | KDM4E (0.67) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL29612371 | 0.72 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPTCASP1 | |
| SCHEMBL379103 | 0.72 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPTCASP1 | |
| Hydrochloric Acid SCHEMBL28521562 | 0.72 | KDM4E (0.65) | KDM4EALDH1A1GAAMAPTCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175551-B1 | ANALGESIC AND ANTIINFLAMMATORY 1,3-DIACYL-2-OXINDOLE COMPOUNDS | PFIZER INC. (US) | 1989-05-10 | — | — | EP | disclosed |