SCHEMBL379103

SCHEMBL379103

Cc1[nH]c2ccccc2c1CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 1.00
MAPT P10636 5/20 1.00
GAA P10253 4/20 1.00
ALDH1A1 P00352 4/20 1.00
CASP1 P29466 1/20 1.00
CASP7 P55210 1/20 1.00
KMT2A Q03164 3/20 0.67
MEN1 O00255 2/20 0.67
EGFR P00533 2/20 0.64
HTT P42858 2/20 0.60
TSHR P16473 1/20 0.60
AKR1C2 P52895 1/20 0.60
POLB P06746 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
CYP3A4 P08684 1/20 0.57
PABPC1 P11940 1/20 0.54
ALOX15 P16050 1/20 0.54
HTR6 P50406 1/20 0.53
HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612371 1.00 KDM4E (1.00) KDM4EMAPTGAAALDH1A1CASP1
Hydrochloric Acid SCHEMBL1372439 0.98 KDM4E (0.97) KDM4EMAPTGAAALDH1A1CASP1
Indole SCHEMBL28345849 0.87 KDM4E (0.76) KDM4EMAPTGAAALDH1A1CASP1
SCHEMBL6980983 0.86 KDM4E (0.74) KDM4EMAPTGAAALDH1A1CASP1
SCHEMBL28092663 0.86 MAPT (0.76) KDM4EMAPTGAAALDH1A1CASP1
SCHEMBL15281758 0.86 MAPT (0.76) KDM4EMAPTGAAALDH1A1CASP1
SCHEMBL30254999 0.85 ALDH1A1 (0.73) KDM4EMAPTGAAALDH1A1CASP1
SCHEMBL3382621 0.85 ALDH1A1 (0.73) KDM4EMAPTGAAALDH1A1CASP1
SCHEMBL7877546 0.85 MAPT (0.73) KDM4EMAPTGAAALDH1A1CASP1
SCHEMBL20037329 0.84 MAPT (0.71) KDM4EMAPTGAAALDH1A1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974758-B Carboxymethyl ketone compound and preparation method thereof 生物岛实验室 2025-06-10 CN claimed
CN-118048666-A Methylsulfonate type pure tin electroplating solution additive and electroplating solution containing same 成都开华化工研究所 2024-05-17 CN claimed
CN-117867608-A Neutral matte pure tin electroplating solution and preparation method thereof 成都开华化工研究所 2024-04-12 CN claimed
CN-115974758-A Carboxymethyl ketone compound and preparation method thereof 生物岛实验室 2023-04-18 CN claimed
CN-113372335-B Phenylalanine derivative containing 1,2, 4-triazole thioether as well as preparation method and application thereof 山东大学 2023-02-24 CN claimed
CN-113372335-A Phenylalanine derivative containing 1,2, 4-triazole thioether and preparation method and application thereof 山东大学 2021-09-10 CN claimed
CN-103705496-B Positively charged water-soluble prodrugs of aryl and heteroaryl propionic acids with fast skin penetration rate 于崇曦 2017-03-01 CN claimed
CN-105218545-A Kallikrein 7 micromolecular inhibitor and preparation method thereof, purposes UNIV HENGYANG NORMAL 2016-01-06 CN claimed
CN-104387371-A 2-((2-methyl-3-indolyl) methyl) benzimidazole derivatives and synthesis thereof UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-03-04 CN claimed
CN-104204798-A Biomarkers for bladder cancer and methods using the same METABOLON INC 2014-12-10 CN claimed
EP-2776832-A1 BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME Metabolon, Inc. (US) 2014-09-17 EP claimed
WO-2013070839-A1 BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME METABOLON, INC. (US) 2013-05-16 WO claimed
EP-1310510-B1 Topologically segregated, encoded solid phase libraries AVENTIS PHARMA INC (US) 2007-07-11 EP claimed
WO-2006076034-A2 STABILIZED TWO COMPONENT SYSTEM FOR CHEMILUMIESCENT ASSAY IN IMMUNODIAGNOSTICS BHANU, KALRA (US) 2006-07-20 WO claimed
US-20050107258-A1 Auxinic analogues of indole-3-acetic acid Life Technologies Corporation 2005-05-19 US claimed
US-20030087762-A1 Auxinic analogues of indole-3-acetic acid LIFE TECHNOLOGIES, INC. 2003-05-08 US claimed
EP-0705279-B1 TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES SELECTIDE CORP (US) 2003-02-19 EP claimed
EP-4172157-B1 CAPSID INHIBITORS FOR THE TREATMENT OF HIV GILEAD SCIENCES INC (US) 2025-11-19 EP disclosed
US-4322355-A Production of 1,3-difunctional compounds NATIONAL DISTILLERS & CHEMICAL CORP. (US) 1982-03-30 US disclosed
US-4118395-A Method for the production of indolyl lactones FRANTSITS WERNER J 1978-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087762-A1 Auxinic analogues of indole-3-acetic acid AADAC, AADAT, AANAT KDM4E 2283/4885MAPT 4454/4885GAA 3723/4885
US-20050107258-A1 Auxinic analogues of indole-3-acetic acid AADAC, AADAT, AANAT KDM4E 2107/4885MAPT 4447/4885GAA 3903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.