Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262349 | 0.81 | ELANE (0.51) | HSD17B10LMNAPTGS2MAPTPKM | |
| SCHEMBL8181798 | 0.77 | ELANE (0.39) | PTGS2MAPTPKMPOLBELANE | |
| SCHEMBL15523219 | 0.75 | ALOX15 (0.47) | MAPTTSHRSMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL15769036 | 0.75 | ME2 (0.41) | MAPTPKMRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4410281 | 0.74 | ESR2 (0.56) | MAPTPKMPOLBGAARAB9A | |
| SCHEMBL10568742 | 0.74 | SMN1; SMN2 (0.56) | HSD17B10PTGS2MAPTPOLBGAA | |
| SCHEMBL329365 | 0.74 | HSD17B10 (0.76) | HSD17B10LMNAPTGS2MAPTPKM | |
| SCHEMBL9158246 | 0.74 | HSD17B10 (0.76) | HSD17B10LMNAPTGS2MAPTPKM | |
| Water SCHEMBL9344643 | 0.72 | HSD17B10 (0.73) | HSD17B10LMNAPTGS2MAPTPKM | |
| SCHEMBL269329 | 0.72 | LMNA (0.80) | HSD17B10LMNAMAPTPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837221-A | ADMINISTERING PORPHYRIN DERIVATIVE TO LOCATE TUMOR, ILLUMINATING WITH LIGHT | EFAMOL LTD. (GB) | 1989-06-06 | — | — | US | disclosed |
| EP-0186962-B1 | PORPHYRINS AND CANCER TREATMENT | EFAMOL LIMITED (GB) | 1989-04-12 | — | — | EP | disclosed |
| EP-0186962-A1 | Porphyrins and cancer treatment | EFAMOL LIMITED (GB) | 1986-07-09 | — | — | EP | disclosed |