Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.45 |
| ▸ | ME1 | P48163 | 1/20 | 0.45 |
| ▸ | ME3 | Q16798 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680192 | 0.92 | ME2 (0.43) | ESR2APPME2ME1ME3 | |
| Hydrochloric Acid SCHEMBL5534014 | 0.90 | ME2 (0.42) | ESR2APPME2ME1ME3 | |
| Hydrochloric Acid SCHEMBL15769036 | 0.88 | ME2 (0.41) | ESR2APPME2ME1ME3 | |
| SCHEMBL28049798 | 0.80 | MMP3 (0.50) | ESR2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL6292615 | 0.80 | MMP3 (0.50) | ESR2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL8179946 | 0.78 | MMP3 (0.48) | ESR2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL9582303 | 0.78 | RPS6KA3 (0.43) | ESR2NPC1MAPTMEN1KMT2A | |
| SCHEMBL27864432 | 0.78 | THRB (0.46) | ESR2APPLTA4HNPC1MAPT | |
| SCHEMBL28436561 | 0.78 | MMP3 (0.48) | ESR2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28865295 | 0.78 | MMP3 (0.48) | ESR2MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071760-B2 | Boron-containing porphyrin compounds and their uses | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090318680-A1 | Boron-Containing Porphyrin Compounds and Their Uses | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2009-12-24 | — | — | US | disclosed |
| EP-1940416-A2 | BORON-CONTAINING PORPHYRIN COMPOUNDS AND THEIR USES | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007050564-A2 | BORON-CONTAINING PORPHYRIN COMPOUNDS AND THEIR USES | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318680-A1 | Boron-Containing Porphyrin Compounds and Their Uses | HMBS, HCCS, PPOX | ESR2 1097/4885APP 3842/4885LTA4H 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.