Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.38 |
| ▸ | PLK1 | P53350 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400985 | 0.81 | ADRA2A (0.53) | ADRA2AABL1GPR84ALDH1A1KCNH3 | |
| SCHEMBL9650900 | 0.80 | ABL1 (0.50) | ABL1GPR84ALDH1A1HCAR3PLK1 | |
| SCHEMBL9187399 | 0.80 | GPR84 (0.51) | ADRA2AABL1GPR84NAAAKCNH3 | |
| SCHEMBL28700733 | 0.79 | ABL1 (0.55) | ADRA2AABL1GPR84ALDH1A1KCNH3 | |
| SCHEMBL3319477 | 0.77 | ABL1 (0.50) | ABL1GPR84ALDH1A1HCAR3PLK1 | |
| SCHEMBL10621223 | 0.77 | GAA (0.46) | ADRA2AABL1GPR84ALDH1A1GAA | |
| SCHEMBL8053981 | 0.76 | GPR84 (0.44) | GPR84HCAR3CISD1NAAA | |
| SCHEMBL28339351 | 0.75 | GAA (0.45) | ADRA2AABL1GPR84ALDH1A1GAA | |
| SCHEMBL6233796 | 0.74 | KCNH3 (0.47) | ADRA2AABL1GPR84ALDH1A1KCNH3 | |
| SCHEMBL8958338 | 0.74 | THRB (0.52) | ADRA2AABL1GPR84ALDH1A1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145920-A | Oxidation resistance, castings, moldings | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| US-5081269-A | OLIGOMER EPOXY RESINS BASED ON CYCLOHEXYLDIPHENOL DERIVATIVES AND REACTION PRODUCTS THEREOF WITH (METH)ACRYLIC ACID AND DIISOCYANATES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |