SCHEMBL105255

SCHEMBL105255

O=C(Cl)c1c(F)cccc1F

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.64
CES1 P23141 4/20 0.64
ALDH1A1 P00352 2/20 0.56
ALOX15 P16050 1/20 0.56
LMNA P02545 1/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
BCHE P06276 1/20 0.44
GAA P10253 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
JAK2 O60674 1/20 0.42
JAK1 P23458 1/20 0.42
TYK2 P29597 1/20 0.42
HTT P42858 1/20 0.42
NOD2 Q9HC29 1/20 0.42
ALB P02768 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15578239 0.97 CES2 (0.61) CES2CES1ALDH1A1ALOX15LMNA
Methylene Chloride SCHEMBL28186741 0.93 CES2 (0.56) CES2CES1ALDH1A1ALOX15LMNA
SCHEMBL28138125 0.91 CES2 (0.54) CES2CES1ALDH1A1ALOX15LMNA
SCHEMBL28111349 0.86 CES2 (0.54) CES2CES1ALDH1A1ALOX15LMNA
SCHEMBL476873 0.86 ALDH1A1 (0.71) CES2CES1ALDH1A1ALOX15LMNA
SCHEMBL9836255 0.86 ALDH1A1 (0.65) CES2CES1ALDH1A1ALOX15LMNA
SCHEMBL8702458 0.85 CES2 (0.59) CES2CES1ALDH1A1ALOX15LMNA
SCHEMBL4089662 0.84 CES2 (0.52) CES2CES1ALDH1A1ALOX15LMNA
SCHEMBL1804943 0.84 CES2 (0.52) CES2CES1ALDH1A1ALOX15LMNA
SCHEMBL29766383 0.84 CES2 (0.52) CES2CES1ALDH1A1ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1898 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994606-A Lithium battery negative electrode binder and preparation method and application thereof 艾迪天目(常州)新材料科技有限公司 2024-11-22 CN claimed
CN-117903168-A Pyrrolo [2,3-d ] thiazole derivatives, and preparation method and application thereof 南开大学 2024-04-19 CN claimed
CN-117186028-A Thiadiazole amide compound containing sulfonate structure, and preparation method and application thereof 贵州大学 2023-12-08 CN claimed
CN-116891443-B Isoindol-1-one derivative and preparation method and application thereof 潍坊医学院 2023-12-01 CN claimed
CN-117105826-A HNO-releasable compound and preparation method thereof 海南大学 2023-11-24 CN claimed
CN-117105897-A HNO donor compound and preparation method thereof 海南大学 2023-11-24 CN claimed
CN-115646223-B Pollution-resistant polyethersulfone ultrafiltration membrane 安徽省海徽化工有限公司 2023-06-27 CN claimed
CN-115703648-A Modified zinc oxide, preparation method thereof and light-emitting diode TCL科技集团股份有限公司 2023-02-17 CN claimed
CN-115646223-A Stain-resistant polyethersulfone ultrafiltration membrane 安徽省海徽化工有限公司 2023-01-31 CN claimed
CN-114230495-B Hydrogenated nitrosyl donor and preparation method thereof 海南大学 2023-01-06 CN claimed
EP-1472217-B1 METHOD FOR PRODUCING PERFLUOROALKANE SULFONIC ACID ESTERS AND THE SALTS THEREOF MERCK PATENT GMBH (DE) 2007-01-24 EP claimed
JP-2005526012-A 2005-09-02 JP claimed
CN-1610660-A Method for producing perfluoroalkane sulfonic acid esters and the salts thereof MERCK PATENT GMBH (DE) 2005-04-27 CN claimed
US-20050085655-A1 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2005-04-21 US claimed
EP-1472217-A2 METHOD FOR PRODUCING PERFLUOROALKANE SULFONIC ACID ESTERS AND THE SALTS THEREOF MERCK PATENT GmbH (DE) 2004-11-03 EP claimed
WO-2003053918-A2 METHOD FOR PRODUCING PERFLUOROALKANE SULFONIC ACID ESTERS AND THE SALTS THEREOF MERCK PATENT GMBH (DE) 2003-07-03 WO claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP claimed
EP-0189960-B1 NOVEL INSECTICIDAL 1,3-THIAZOLE DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-04-24 EP claimed
EP-0189960-A2 Novel insecticidal 1,3-thiazole derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-08-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085655-A1 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid PFKFB2, PFKFB3, PHOSPHO1 CES2 167/4885CES1 504/4885ALDH1A1 1147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.