Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10523532 | 1.00 | ADRA1A (0.57) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL13996935 | 0.81 | CYP1A2 (0.55) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL14442995 | 0.81 | CYP1A2 (0.55) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL14442996 | 0.81 | CYP1A2 (0.55) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL8264659 | 0.77 | KMT2A (0.59) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL10014392 | 0.77 | KMT2A (0.59) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL14523334 | 0.77 | KMT2A (0.59) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL5685898 | 0.76 | SIGMAR1 (0.68) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL20847996 | 0.76 | SIGMAR1 (0.68) | ADRA1AOPRK1CYP1A2CYP2C19TSHR | |
| SCHEMBL5685881 | 0.76 | SIGMAR1 (0.68) | ADRA1AOPRK1CYP1A2CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318889-A2 | Method for treatment of dyslipidemia in humans | SCHERING CORPORATION (US) | 1989-06-07 | — | — | EP | claimed |