Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910843 | 0.93 | LTA4H (0.47) | SMN1; SMN2NPC1RAB9ATSHRTHRB | |
| SCHEMBL10526825 | 0.91 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9ATSHRTHRB | |
| SCHEMBL11003739 | 0.84 | TDP1 (0.49) | SMN1; SMN2TSHRTDP1ALOX5MEN1 | |
| SCHEMBL11231795 | 0.84 | TDP1 (0.47) | SMN1; SMN2TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7576079 | 0.83 | THRB (0.62) | SMN1; SMN2NPC1RAB9ATSHRTHRB | |
| SCHEMBL10964380 | 0.81 | LTA4H (0.45) | SMN1; SMN2NPC1RAB9ATDP1ALOX5 | |
| SCHEMBL9176883 | 0.80 | LTA4H (0.46) | SMN1; SMN2NPC1RAB9ATSHRTHRB | |
| SCHEMBL27940429 | 0.80 | THRB (0.59) | SMN1; SMN2NPC1RAB9ATSHRTHRB | |
| SCHEMBL10336969 | 0.80 | THRB (0.59) | SMN1; SMN2NPC1RAB9ATSHRTHRB | |
| SCHEMBL10908923 | 0.79 | HPGD (0.46) | NPC1RAB9ATDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845235-A | Pyrroline derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1989-07-04 | — | — | US | disclosed |