Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526846 | 0.93 | SMN1; SMN2 (0.53) | LTA4HSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL10526825 | 0.85 | NPC1 (0.50) | LTA4HSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL10964380 | 0.82 | LTA4H (0.45) | LTA4HSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL11003739 | 0.81 | TDP1 (0.49) | LTA4HSMN1; SMN2TSHRTDP1ALOX5 | |
| SCHEMBL3640377 | 0.81 | THRB (0.56) | LTA4HSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL11675033 | 0.81 | LTA4H (0.50) | LTA4HALDH1A1HTTCYP1A2CYP2C9 | |
| SCHEMBL11822821 | 0.81 | SMN1; SMN2 (0.47) | LTA4HSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9331718 | 0.80 | SMN1; SMN2 (0.51) | LTA4HSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL10525189 | 0.79 | SMN1; SMN2 (0.67) | LTA4HSMN1; SMN2ALOX5ALDH1A1TP53 | |
| SCHEMBL12088221 | 0.79 | CNR2 (0.46) | SMN1; SMN2RAB9ATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085811-B1 | 2-(PHENYLMETHYLENE)CYCLOALKYLAMINES | THE UPJOHN COMPANY (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4564673-A | 3-Cyano-5-nitrothiophene anilino monoazo dye for synthetic fibers | RESEARCH ASSOCIATION OF SYNTHETIC DYESTUFFS (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0109857-A1 | Monoazo dye for synthetic fibers | RESEARCH ASSOCIATION OF SYNTHETIC DYESTUFFS (JP) | 1984-05-30 | — | — | EP | disclosed |