SCHEMBL1053015

SCHEMBL1053015

O=[C]CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.54
SLC6A9 P48067 1/20 0.39
S1PR1 P21453 1/20 0.34
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.31
ALDH1A1 P00352 3/20 0.31
STAT6 P42226 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.31
ITGB3 P05106 2/20 0.31
ITGA2B P08514 2/20 0.31
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22344791 1.00 HSD17B10 (0.54) HSD17B10SLC6A9S1PR1KDM4EGAA
Tetraxetan SCHEMBL2017956 0.83 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1KDM4EGAA
SCHEMBL3660521 0.83
SCHEMBL3503521 0.83 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1KDM4EGAA
Tetraxetan SCHEMBL2635294 0.83 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1KDM4EGAA
SCHEMBL6848102 0.83 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1KDM4EGAA
Tetraxetan SCHEMBL18018 0.83 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1KDM4EGAA
SCHEMBL173508 0.83 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1KDM4EGAA
SCHEMBL321989 0.83 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1KDM4EGAA
SCHEMBL6744121 0.83 HSD17B10 (0.64) HSD17B10SLC6A9S1PR1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120134922-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-31 US claimed
US-20120134931-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-31 US claimed
EP-2453926-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE The Regents of the University of California (US) 2012-05-23 EP claimed
WO-2011008996-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO claimed
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES ANTAROS MEDICAL AB (SE) 2023-04-27 US disclosed
CN-115348876-A Selective GIP receptor agonists comprising chelating moieties for imaging and therapeutic purposes 安塔罗斯医疗公司 2022-11-15 CN disclosed
US-11246940-B2 Peptides whose uptake in cells is controllable THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-02-15 US disclosed
CN-113908296-A Compositions and methods utilizing lysophosphatidylcholine scaffolds 新加坡国立大学 2022-01-11 CN disclosed
CN-105764917-B Compositions and methods utilizing lysophosphatidylcholine scaffolds 新加坡国立大学 2021-10-08 CN disclosed
US-11046743-B2 Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes ANTAROS MEDICAL AB (SE) 2021-06-29 US disclosed
EP-3760638-A2 COMPOSITIONS AND METHODS UTILIZING LYSOPHOSPHATIDYLCHOLINE SCAFFOLDS National University of Singapore (SG) 2021-01-06 EP disclosed
EP-3389697-B1 SELECTIVE GLUCAGON RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING PURPOSES ANTAROS MEDICAL AB (SE) 2020-12-16 EP disclosed
US-20130136691-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2013-05-30 US disclosed
US-20120134931-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-31 US disclosed
US-20120134922-A1 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-31 US disclosed
EP-2453926-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE The Regents of the University of California (US) 2012-05-23 EP disclosed
EP-2454271-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE The Regents of the University of California (US) 2012-05-23 EP disclosed
WO-2011008996-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO disclosed
WO-2011008992-A2 PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-20 WO disclosed
EP-0722442-A1 POLYAZACYCLOALKANES AS DICHELANTS NYCOMED SALUTAR, INC. (US) 1996-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130136691-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS GRPR, GIPR, GHRHR HSD17B10 3947/4885SLC6A9 1703/4885S1PR1 751/4885
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES GIPR, GRPR, GLP1R HSD17B10 4682/4885SLC6A9 934/4885S1PR1 460/4885
US-11046743-B2 Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes GLP1R, GCGR, GIPR HSD17B10 4571/4885SLC6A9 914/4885S1PR1 899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.