SCHEMBL10530188

SCHEMBL10530188

Nc1ccc(S(=O)(=O)Nc2cccc3ccc(OP(N)(N)=O)cc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.47
▸ KMT2A Q03164 5/20 0.47
▸ HTR6 P50406 2/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ RECQL P46063 1/20 0.46
▸ PLAU P00749 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ CA1 P00915 2/20 0.43
▸ CA2 P00918 2/20 0.43
▸ CA9 Q16790 1/20 0.43
▸ LMNA P02545 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ KEAP1 Q14145 3/20 0.41
▸ GLO1 Q04760 2/20 0.41
▸ NFE2L2 Q16236 2/20 0.40
▸ SQSTM1 Q13501 1/20 0.40
▸ SLC40A1 Q9NP59 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11411080 0.87 NFKBIA (0.49) MEN1KMT2ATDP1RECQLPLAU
SCHEMBL29962236 0.79 KMT2A (0.57) MEN1KMT2AHTR6TDP1RECQL
SCHEMBL11437266 0.78 FFAR4 (0.53) MEN1KMT2AHTR6TDP1ALDH1A1
SCHEMBL11438430 0.78 HTR6 (0.62) MEN1KMT2AHTR6ALDH1A1CA1
SCHEMBL164503 0.77 RECQL (0.76) MEN1KMT2AHTR6TDP1RECQL
SCHEMBL10874195 0.75 CA1 (0.55) MEN1KMT2AHTR6TDP1CA1
SCHEMBL11438160 0.74 CA1 (0.59) MEN1KMT2AHTR6ALDH1A1MAPT
SCHEMBL9942077 0.71 RECQL (0.71) MEN1KMT2AHTR6TDP1RECQL
SCHEMBL17849555 0.69 KEAP1 (0.62) MEN1KMT2ATDP1RECQLALDH1A1
SCHEMBL17849561 0.69 KMT2A (0.59) MEN1KMT2AHTR6TDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4225526-A 8-[(4-Aminophenyl)sulfonyl]amino-2-naphthalenyl phosphorodiamidate MORTON-NORWICH PRODUCTS, INC. (US) 1980-09-30 — — US claimed
US-4824783-A FERTILIZERS ENICHEM S.P.A. (IT) 1989-04-25 — — US disclosed
US-4696693-A Oxidized sulfur derivatives of diaminophosphinyl compounds as urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1987-09-29 — — US disclosed
US-4629491-A PLANT GROWTH REGULATORS ALLIED CORPORATION (US) 1986-12-16 — — US disclosed
US-4624695-A FERTILIZERS ALLIED CORPORATION (US) 1986-11-25 — — US disclosed
EP-0119487-B1 NOVEL N-ALIPHATIC AND N,N-ALIPHATIC PHOSPHORIC TRIAMIDE UREASE INHIBITORS AND UREASE INHIBITED UREA BASED FERTILIZER COMPOSITIONS ALLIED CORPORATION (US) 1986-07-16 — — EP disclosed
US-4540428-A Phosphorotriamidate urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-09-10 — — US disclosed
US-4539037-A Urease inhibited urea based fertilizer compositions containing N-aryl-N-aliphatic phosphorotriamide compounds ALLIED CORPORATION (US) 1985-09-03 — — US disclosed
US-4537614-A PLANT GROWTH REGULATORS ALLIED CORPORATION (US) 1985-08-27 — — US disclosed
US-4530714-A Capable of forming urea under use conditions ALLIED CORPORATION (US) 1985-07-23 — — US disclosed
US-4517002-A Phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-05-14 — — US disclosed
US-4517007-A Phosphoroamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-05-14 — — US disclosed
US-4517003-A N-acyl phosphoric triamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-05-14 — — US disclosed
US-4517004-A Aryl phosphoric triamide and aryl phosphorodiamidate urease and nitrification inhibitors and urease and nitrification inhibited urea and reduced nitrogen based fertilizer compositions ALLIED CORPORATION (US) 1985-05-14 — — US disclosed
EP-0119487-A1 Novel N-aliphatic and N,N-aliphatic phosphoric triamide urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1984-09-26 — — EP disclosed
EP-0119494-A1 Urease inhibited urea based fertilizer compositions containing phosphorus compounds ALLIED CORPORATION (US) 1984-09-26 — — EP disclosed
EP-0119495-A1 S-aryl and S-aliphatic diamidophosphorothiolates as urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1984-09-26 — — EP disclosed
US-4225526-A 8-[(4-Aminophenyl)sulfonyl]amino-2-naphthalenyl phosphorodiamidate MORTON-NORWICH PRODUCTS, INC. (US) 1980-09-30 — — US disclosed
US-4225526-A 8-[(4-Aminophenyl)sulfonyl]amino-2-naphthalenyl phosphorodiamidate MORTON-NORWICH PRODUCTS, INC. (US) 1980-09-30 — — US disclosed
US-4225526-A 8-[(4-Aminophenyl)sulfonyl]amino-2-naphthalenyl phosphorodiamidate MORTON-NORWICH PRODUCTS, INC. (US) 1980-09-30 — — US disclosed
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