Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438430 | 0.83 | HTR6 (0.62) | CA1CA2CA9HTTKMT2A | |
| SCHEMBL11443736 | 0.83 | CA2 (0.63) | CA1CA2CA9HTTKMT2A | |
| SCHEMBL18386666 | 0.82 | CA1 (0.69) | CA1CA2CA9HTTKMT2A | |
| SCHEMBL11793140 | 0.82 | CA1 (0.85) | CA1CA2CA9HTTKMT2A | |
| SCHEMBL540915 | 0.82 | CA1 (0.85) | CA1CA2CA9HTTKMT2A | |
| SCHEMBL29118855 | 0.80 | LMNA (0.73) | CA1CA2CA9HTTKMT2A | |
| SCHEMBL2240982 | 0.80 | LMNA (0.73) | CA1CA2CA9HTTKMT2A | |
| SCHEMBL11437266 | 0.78 | FFAR4 (0.53) | CA1CA2CA9KMT2AKEAP1 | |
| SCHEMBL19603195 | 0.77 | CA1 (0.76) | CA1CA2CA9HTTKMT2A | |
| SCHEMBL12167748 | 0.76 | PGR (0.76) | CA1CA2CA9HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222948-A | [[(4-Aminophenyl)sulfonyl]amino]phenyl phosphorodiamidates | MORTON-NORWICH PRODUCTS, INC. (US) | 1980-09-16 | — | — | US | claimed |
| US-4222948-A | [[(4-Aminophenyl)sulfonyl]amino]phenyl phosphorodiamidates | MORTON-NORWICH PRODUCTS, INC. (US) | 1980-09-16 | — | — | US | disclosed |