Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PKLR | P30613 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17849555 | 0.90 | KEAP1 (0.62) | KMT2AMEN1TDP1KEAP1NFE2L2 | |
| SCHEMBL9942077 | 0.87 | RECQL (0.71) | KMT2AMEN1TDP1GLO1HSD11B1 | |
| SCHEMBL16187949 | 0.83 | KMT2A (0.60) | KMT2AMEN1TDP1GLO1HSD11B1 | |
| SCHEMBL17849565 | 0.83 | KMT2A (0.53) | KMT2AMEN1TDP1KEAP1NFE2L2 | |
| SCHEMBL7573136 | 0.81 | KEAP1 (0.76) | KMT2AMEN1TDP1KEAP1NFE2L2 | |
| SCHEMBL17849571 | 0.81 | KAT6A (0.59) | KMT2AMEN1TDP1GLO1HSD11B1 | |
| SCHEMBL9942107 | 0.81 | HSD17B2 (0.61) | KMT2AMEN1HSD11B1PKMPKLR | |
| SCHEMBL28326534 | 0.81 | HSD17B2 (0.61) | KMT2AMEN1HSD11B1PKMPKLR | |
| SCHEMBL808090 | 0.80 | HKDC1 (0.61) | KMT2AMEN1TDP1KEAP1NFE2L2 | |
| SCHEMBL16210882 | 0.78 | MEN1 (0.59) | KMT2AMEN1TDP1GLO1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |