Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335253 | 0.74 | POLB (0.46) | HTTTDP1POLBLMNASMN1; SMN2 | |
| SCHEMBL1618548 | 0.73 | TDP1 (0.48) | HTTTDP1POLBLMNASMN1; SMN2 | |
| SCHEMBL22475379 | 0.71 | TDP1 (0.46) | HTTTDP1POLBLMNASMN1; SMN2 | |
| SCHEMBL9092595 | 0.71 | TDP1 (0.46) | HTTTDP1POLBLMNASMN1; SMN2 | |
| SCHEMBL2794591 | 0.71 | TDP1 (0.46) | HTTTDP1POLBLMNASMN1; SMN2 | |
| SCHEMBL9677089 | 0.70 | TDP1 (0.39) | HTTTDP1POLBLMNASMN1; SMN2 | |
| SCHEMBL2802532 | 0.69 | TDP1 (0.44) | HTTTDP1POLBLMNASMN1; SMN2 | |
| SCHEMBL1387982 | 0.67 | PDE10A (0.54) | HTTPOLBLMNAPDE10AALDH1A1 | |
| SCHEMBL9560914 | 0.67 | TDP1 (0.46) | HTTTDP1POLBLMNASMN1; SMN2 | |
| SCHEMBL9236926 | 0.67 | TDP1 (0.42) | HTTTDP1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873346-A | BRONCHODILATORS, TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1989-10-10 | — | — | US | disclosed |