Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794591 | 0.80 | TDP1 (0.46) | TDP1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL636638 | 0.80 | CYP11B1 (0.50) | TDP1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL1618548 | 0.80 | TDP1 (0.48) | TDP1LMNASMN1; SMN2HTTCYP11B1 | |
| SCHEMBL9236926 | 0.79 | TDP1 (0.42) | TDP1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL2802532 | 0.79 | TDP1 (0.44) | TDP1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL22475379 | 0.77 | TDP1 (0.46) | TDP1LMNASMN1; SMN2HTTCYP11B1 | |
| SCHEMBL9092595 | 0.77 | TDP1 (0.46) | TDP1LMNASMN1; SMN2HTTCYP11B1 | |
| SCHEMBL630973 | 0.76 | POLB (0.43) | TDP1LMNASMN1; SMN2HTTTSHR | |
| SCHEMBL10587534 | 0.72 | POLB (0.39) | TDP1LMNASMN1; SMN2HTTCYP11B1 | |
| SCHEMBL5984224 | 0.72 | RAB9A (0.41) | SMN1; SMN2HTTPOLBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548103-A1 | USE OF PYRIDYLMETHYLSULPHINYL-1H-BENZIMIDAZOLE DERIVATES IN THE TREATMENT OF ILLNESSES CAUSED BY HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004898-A1 | USE OF PYRIDYLMETHYLSULPHINYL-1H-BENZIMIDAZOLE DERIVATES IN THE TREATMENT OF ILLNESSES CAUSED BY HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-04-02 | — | — | WO | disclosed |