Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802532 | 0.98 | TDP1 (0.44) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL1618548 | 0.84 | TDP1 (0.48) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL22475379 | 0.81 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL9092595 | 0.81 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2POLB | |
| SCHEMBL9560914 | 0.80 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL3335253 | 0.74 | POLB (0.46) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL636638 | 0.74 | CYP11B1 (0.50) | TDP1HTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9236926 | 0.73 | TDP1 (0.42) | TDP1HTTLMNASMN1; SMN2POLB | |
| SCHEMBL9677089 | 0.73 | TDP1 (0.39) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL10531813 | 0.71 | HTT (0.37) | TDP1HTTLMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947967-A | A kind of preparation method of Lansoprazole | 威海迪素制药有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-108947967-A | A kind of preparation method of Lansoprazole | 威海迪素制药有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-107141280-A | A kind of preparation method of Dexlansoprazole | 长沙康普大药房有限责任公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-104546718-B | A kind of long circulating Rabeprazole liposome composition and its preparation method and application | 江苏奥赛康药业股份有限公司 | 2017-06-06 | — | — | CN | disclosed |
| CN-105510511-B | HPLC (High Performance Liquid Chromatography) separation and detection method of 2-aminobutanol enantiomer | 河北科技大学 | 2017-04-12 | — | — | CN | disclosed |
| CN-103965166-B | Rabeprazole intermediate impurities 2-{ [4-(3-methoxy propoxy)-3-oxide of mathylpyridine-2-base] methyl sulfur } preparation method of-1H-benzimidazole | 东南大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-101524336-B | Dosage forms for oral administration of magnesium salt of pantoprazole | NICOMEDE CO LTD | 2013-12-18 | — | — | CN | disclosed |
| WO-2010146428-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF RABEPRAZOLE | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2010-12-23 | — | — | WO | disclosed |
| CN-101524336-A | Dosage forms for oral administration of magnesium salt of pantoprazole | NICOMEDE CO LTD (DE) | 2009-09-09 | — | — | CN | disclosed |
| CN-100536844-C | Pharmaceutical paste comprising acid-labile activeingredient | ALTANA PHARMA AG (DE) | 2009-09-09 | — | — | CN | disclosed |
| CN-100335040-C | Rapidly disintegrating tablet comprising acid-sensitive active ingredient | ALTANA PHARMA AG (DE) | 2007-09-05 | — | — | CN | disclosed |
| CN-1822835-A | Alkaline salts of proton pump inhibitors | ALTANA PHARMA AG (DE) | 2006-08-23 | — | — | CN | disclosed |
| CN-1784227-A | Dosage form comprising pantoprazole as active ingredient | ALTANA PHARMA AG (DE) | 2006-06-07 | — | — | CN | disclosed |
| EP-1615624-A2 | ORAL PHARMACEUTICAL PREPARATION COMPRISING A PROTON PUMP ANTAGONIST AND A BASIC EXCIPIENT | ALTANA Pharma AG (DE) | 2006-01-18 | — | — | EP | disclosed |
| CN-1541091-A | Pharmaceutical prepn. in form of suspension comprising acid-labile active ingredient | ��̹��ҽҩ��˾ | 2004-10-27 | — | — | CN | disclosed |
| WO-2004089342-A2 | ORAL PHARMACEUTICAL PREPARATION COMPRISING A PROTON PUMP ANTAGONIST AND A BASIC EXIPIENT | ALTANA PHARMA AG (DE) | 2004-10-21 | — | — | WO | disclosed |
| CN-1479613-A | rapidly disintegrating tablet containing acid-sensitive active ingredient | ��̹��ҽҩ��˾ | 2004-03-03 | — | — | CN | disclosed |
| CN-1479611-A | Pharmaceutical paste comprising acid-labile activeingredient | ��̹��ҽҩ��˾ | 2004-03-03 | — | — | CN | disclosed |
| CN-1361683-A | Novel formulations and pharmaceutical forms containing an acid-labile active compound | BYK GULDEN RAUMBERG CHEMIE GMB (DE) | 2002-07-31 | — | — | CN | disclosed |
| CN-1251035-A | Gastrointestinal mucosa-adherent pharmaceutical composition | TAKEDA CHEMCAL IND LTD (JP) | 2000-04-19 | — | — | CN | disclosed |