Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794591 | 0.98 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL1618548 | 0.82 | TDP1 (0.48) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL9092595 | 0.79 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2POLB | |
| SCHEMBL22475379 | 0.79 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL9560914 | 0.79 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL3335253 | 0.73 | POLB (0.46) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL636638 | 0.73 | CYP11B1 (0.50) | TDP1HTTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9236926 | 0.71 | TDP1 (0.42) | TDP1HTTLMNASMN1; SMN2POLB | |
| SCHEMBL9677089 | 0.71 | TDP1 (0.39) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL10531813 | 0.69 | HTT (0.37) | TDP1HTTLMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111429-A | Dextrobeprazole sodium compound and pharmaceutical composition thereof | 南京海润医药有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-109111428-A | Dextro-rabeprazole sodium compound and pharmaceutical composition thereof | 南京海润医药有限公司 | 2019-01-01 | — | — | CN | disclosed |
| WO-2010146428-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF RABEPRAZOLE | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2010-12-23 | — | — | WO | disclosed |