Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531419 | 0.81 | ALDH1A1 (0.40) | ABL1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL15075928 | 0.81 | ABL1 (0.54) | ABL1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL21257568 | 0.81 | ABL1 (0.40) | ABL1ALDH1A1PKMMAPTMCOLN3 | |
| SCHEMBL10533223 | 0.78 | NR1D1 (0.51) | ALDH1A1NR1D1PKMMAPTPOLB | |
| SCHEMBL12605962 | 0.74 | MEP1B (0.41) | ALDH1A1NR1D1MAPTMEP1BGAA | |
| SCHEMBL16370082 | 0.72 | SLC6A4 (0.58) | ALDH1A1KDM4EGAAKMT2AHPGD | |
| SCHEMBL26685333 | 0.72 | ABL1 (0.50) | ABL1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL25346099 | 0.71 | LMNA (0.46) | ALDH1A1MAPTKDM4EGAAPOLB | |
| SCHEMBL21257783 | 0.71 | ALDH1A1 (0.39) | ABL1ALDH1A1PKMMAPTMCOLN3 | |
| SCHEMBL29758099 | 0.71 | CYP3A4 (0.54) | ABL1ALDH1A1MAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989006980-A1 | RADIOPHARMACEUTICALS | UNIVERSITY OF QUEENSLAND (AU) | 1989-08-10 | — | — | WO | claimed |
| WO-1989006980-A1 | RADIOPHARMACEUTICALS | UNIVERSITY OF QUEENSLAND (AU) | 1989-08-10 | — | — | WO | disclosed |