Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 8/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879818 | 0.73 | HTT (0.48) | SMN1; SMN2TDP1HTTPOLBMEN1 | |
| SCHEMBL10962344 | 0.72 | POLB (0.49) | SMN1; SMN2TDP1HTTPOLBMEN1 | |
| SCHEMBL8013907 | 0.72 | TDP1 (0.52) | SMN1; SMN2TDP1HTTPOLBMEN1 | |
| SCHEMBL273486 | 0.72 | TDP1 (0.52) | SMN1; SMN2TDP1HTTPOLBMEN1 | |
| SCHEMBL1387982 | 0.69 | PDE10A (0.54) | HTTPOLBFGFR1 | |
| SCHEMBL20683088 | 0.69 | TDP1 (0.48) | SMN1; SMN2TDP1HTTPOLBMEN1 | |
| SCHEMBL6381049 | 0.69 | TDP1 (0.48) | SMN1; SMN2TDP1HTTPOLBMEN1 | |
| SCHEMBL28067710 | 0.68 | CYP11B1 (0.46) | SMN1; SMN2TDP1HTTPOLBMEN1 | |
| SCHEMBL6547293 | 0.66 | TDP1 (0.39) | SMN1; SMN2TDP1HTTPOLBMEN1 | |
| SCHEMBL10437253 | 0.66 | CYP11B1 (0.57) | SMN1; SMN2TDP1HTTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873346-A | BRONCHODILATORS, TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1989-10-10 | — | — | US | disclosed |