Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 5/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | PRKACA | P17612 | 2/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.34 |
| ▸ | APC | P25054 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10896726 | 0.77 | ADCY5 (0.40) | ADCY5ADORA2ATAAR1 | |
| SCHEMBL10902555 | 0.77 | ADCY5 (0.40) | ADCY5ADORA2ATAAR1 | |
| SCHEMBL9560980 | 0.76 | MARS1 (0.37) | ADCY5PLA2G2A | |
| SCHEMBL8466911 | 0.75 | ADCY5 (0.37) | ADCY5PRKACAPLA2G2AADORA2A | |
| SCHEMBL10534213 | 0.73 | NPY4R (0.36) | ROCK2PRKACAAKT3 | |
| SCHEMBL9561486 | 0.72 | PRMT5 (0.39) | ADCY5PRKACAPLA2G2A | |
| SCHEMBL11252087 | 0.72 | NOD2 (0.41) | APCPTPN1ERAP2ERAP1LNPEP | |
| SCHEMBL9561462 | 0.72 | CPB1 (0.40) | ADCY5ROCK2PRKACAAKT3 | |
| SCHEMBL9561069 | 0.72 | CPB1 (0.40) | ADCY5ROCK2PRKACAAKT3 | |
| SCHEMBL9561414 | 0.72 | NPY4R (0.40) | ADCY5PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | claimed |
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | claimed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | claimed |
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | disclosed |