Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532871 | 0.78 | ALOX5 (0.44) | HSP90AA1ALDH1A1HTTNPSR1CA1 | |
| SCHEMBL4307777 | 0.77 | CACNA1G (0.54) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL10655279 | 0.76 | CA2 (0.44) | HSP90AA1ALDH1A1HTTNPSR1CA1 | |
| SCHEMBL29033977 | 0.72 | KDM1A (0.53) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL30502860 | 0.72 | KDM1A (0.53) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL10653040 | 0.72 | MAPT (0.44) | ALDH1A1HTTNPSR1CA1CA2 | |
| SCHEMBL30502867 | 0.71 | KDM1A (0.54) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL29033973 | 0.71 | KDM1A (0.54) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL10656863 | 0.71 | CA1 (0.37) | HDAC1HDAC2HDAC8HDAC6HDAC5 | |
| SCHEMBL8849761 | 0.71 | CA2 (0.66) | HDAC2HDAC8ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808620-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIALLERGENS, ANTIARTHRITIC, ANTIRHEUMATIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-02-28 | — | — | US | disclosed |