SCHEMBL105343

SCHEMBL105343

CC(C(=O)O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.39
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TP53 P04637 1/20 0.32
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDK1 Q15118 2/20 0.31
PDK2 Q15119 2/20 0.31
PDK3 Q15120 2/20 0.31
PDK4 Q16654 2/20 0.31
TET2 Q6N021 1/20 0.31
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10870961 0.97 ALDH1A1 (0.42) ALDH1A1TSHRTHRBCYP2D6CYP2C19
Fluoride SCHEMBL4806824 0.97 ALDH1A1 (0.42) ALDH1A1TSHRTHRBCYP2D6CYP2C19
SCHEMBL10873671 0.97 ALDH1A1 (0.42) ALDH1A1TSHRTHRBCYP2D6CYP2C19
SCHEMBL16675254 0.83 TSHR (0.36) ALDH1A1TSHRTHRBCYP2D6CYP2C19
SCHEMBL249117 0.74
SCHEMBL134556 0.74
SCHEMBL568925 0.73 ALDH1A1 (0.53) ALDH1A1TSHRTHRBPDK1PDK2
SCHEMBL9419958 0.73 ALDH1A1 (0.44) ALDH1A1TSHRTHRBCYP2D6CYP2C19
SCHEMBL568924 0.73 ALDH1A1 (0.53) ALDH1A1TSHRTHRBPDK1PDK2
SCHEMBL421936 0.73 MEN1 (0.31) ALDH1A1TSHRMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 541 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110770271-B Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2023-04-18 CN claimed
EP-3580259-B1 ROBUST SUPERHYDROPHOBIC MATERIAL AND COATING UCL BUSINESS LTD (GB) 2022-07-27 EP claimed
US-20200123392-A1 Robust Superhydrophobic Material and Coating UCL BUSINESS LTD (GB) 2020-04-23 US claimed
EP-3635022-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME Etna-Tec, Ltd (US) 2020-04-15 EP claimed
CN-110770271-A Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same 埃特纳科技有限公司 2020-02-07 CN claimed
US-20180334416-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ETNA-TEC, LTD. 2018-11-22 US claimed
WO-2018213850-A1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA-TEC, LTD (US) 2018-11-22 WO claimed
WO-2018146252-A1 ROBUST SUPERHYDROPHOBIC MATERIAL AND COATING UCL BUSINESS PLC (GB) 2018-08-16 WO claimed
US-10040732-B2 Process for the production of biaryl compounds DSM IP ASSETS B.V. (NL) 2018-08-07 US claimed
EP-3169651-B1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS BV (NL) 2018-06-20 EP claimed
US-20170210681-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS B.V. (NL) 2017-07-27 US claimed
EP-3169651-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP Assets B.V. (NL) 2017-05-24 EP claimed
CN-106536455-A Process for the production of biaryl compounds 帝斯曼知识产权资产管理有限公司 2017-03-22 CN claimed
WO-2016008931-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DSM IP ASSETS B.V. (NL) 2016-01-21 WO claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210681-A1 PROCESS FOR THE PRODUCTION OF BIARYL COMPOUNDS DDT, COASY, ALDH3A1 ALDH1A1 52/4885TSHR 4029/4885THRB 3472/4885
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product CD38, PARP9, MCCC2 ALDH1A1 737/4885TSHR 4705/4885THRB 3530/4885
US-10040732-B2 Process for the production of biaryl compounds DDT, COASY, ALDH3A1 ALDH1A1 52/4885TSHR 4029/4885THRB 3472/4885
US-20180334416-A1 Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same ALKBH3, FTO, ALK ALDH1A1 98/4885TSHR 2090/4885THRB 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.